D Panthenol (Vitamin B5) Studies have show D-panthenol promotes stimulation of epithelization, granulation, mitigation of itching and has an anti-inflammatory effect.  When used in formulations over the course of three to four weeks, it has the potential to improve the appearance of the skin, including dryness, roughness, scaling, pruritus and erythema.  Further, its moisturizing properties improve stratum corneum hydration, reducing transepidermal water loss and maintaining skin elasticity and softness. Panthenol also works with DMAE in the production of acetylcholine which firms and tones the skin.